I have bought a book from David Allen about “How getting thigs done” (http://www.amazon.de/Getting-Things-Done-Stress-Free-Productivity/dp/0142000280) as workload and complexity was getting worse. With this book I found ways to manage my work and todos in a better manner than “FIFO”.
Now with a year past, I stumbled across a link from David Allen about Tracks – a webbased tool based on the methods described in the book.
Big upsite, there is a standalone version for linux/windows/mac. Downside, it is not multi-user capable, meaning I cannot assign tasks to people within my organisation.
We are currently testing the application, but it does look very helpful.
PS. A good howto for debian users :http://ubuntuforums.org/showthread.php?t=1580690